New Charged Aerosol Detector Designed for Ultra-High Performance Liquid Chromatography (UHPLC) Applications; Company will also Launch New Coulometric UHPLC Cell
CHELMSFORD, Mass., March 2 /PRNewswire/ -- ESA Biosciences, Inc., a Magellan Biosciences company and leader in novel HPLC systems that improve results for pharmaceutical development and QA/QC, life science, and analytical-chemistry customers worldwide, will launch a new, ultra-high-performance version of its award-winning Corona CAD at Pittcon 2009. Fully stackable, with the utmost in sensitivity and flexibility, ESA designed the Corona ultra so that scientists can take full advantage of the speed and increased resolution that UHPLC systems are bringing to today's challenging applications. Pittcon 2009 will be held March 9-12 at McCormick Place in Chicago, Illinois.
Commenting on the new Corona ultra detector, Jasmine Gruia-Gray, PhD, president of ESA's life science tools business, said, "Drug formulations are increasingly complex; analytical scientists can't afford to miss even the lowest concentration of impurities, which is why our Corona CAD has become a key analytical tool in the pharmaceutical industry. Breakdown products and impurities may lose their UV response, so they're easy to overlook with other detectors. Our charged aerosol detection technology lets you see any non-volatile analyte, even those without a chromophore. Speed is also important and the leading pharmaceutical development and QA/QC operations have been migrating to a UHPLC environment. We designed the new Corona ultra to customer specifications. It delivers the increased resolution and performance that other detectors can't match, with the cost and time savings of high-speed analysis - plus, it's rugged and stackable so it fits easily in any lab - no additional bench space necessary."
Besides excellent sensitivity, the Corona ultra shows consistent inter-analyte response independent of chemical structure. This breakthrough detector can effectively analyze a wide diversity of chemical structures and important classes of molecules - from small organic molecules, proteins and peptides, to ions, carbohydrates, lipids, and polymers. The Corona ultra makes methods development, validation, and transfer fast and easy for a wide range of life-science research applications and industries: pharmaceutical, chemical, polymer, food and beverage, biofuel, oils, petrochemical, and more. For more information, visit www.corona-ultra.com.
Corona ultra features & benefits
UHPLC compatible -- Faster chromatography methods with higher resolution
-- Compatible with traditional HPLC
-- Maintains high resolution while reducing analysis
Time
Heated/Cooled -- Flexibility to develop methods for various types of
nebulizer analytes
-- More precise nebulization temperature control
Dynamic range Enabling detection over four orders of magnitude e.g.
API and impurities in the same run
Sensitivity 10 ng on column, enabling detection of impurities
<0.05%
Customer Care ESA provides you with the highest standard in customer
Program care to ensure customer confidence, security,
knowledge, and support
In addition to the Corona ultra, visitors to the ESA booth #1080 will see other versatile, applications-focused systems designed to help scientists do their jobs better, faster, and easier. ESA will show a range of electrochemical cells, including the brand new ultra Analytical Cell (PittCon 2009 launch), a coulometric cell designed for use with UHPLC systems. ESA's high-efficiency, high-capacity synthesis cell will also be featured. It simplifies generation of analytes, possible degradants, or product for hard-to-make, or unavailable drug-synthesis compounds, and is ideal for producing compounds for NMR or mass spectrometry analysis or biological studies. ESA systems are easy to implement, easy to run, and easy to maintain - so scientists can spend their precious time doing research with their instruments, not on their instruments.
Pittcon attendees should be sure to stop by the ESA Knowledge Center at booth #1080. There, visitors can sit down with an ESA scientist to discuss their specific analytical challenges and customer-care needs - or peruse detailed technical presentations on a variety of applications. The company will also present 15 posters at Pittcon, listed below.
About ESA Life Science Tools (www.esainc.com)
A Magellan Biosciences business, ESA Life Science Tools enables answers to pressing analytical challenges for analytical and diagnostics laboratories worldwide. Leaders in HPLC detection, ESA's flexible, applications-focused systems combine specialty detectors with optimized components and consumables - all designed to achieve maximum performance. ESA's Customer Care experts deliver the highest standard of service to ensure customer confidence, security, knowledge, and support.
ESA Pittcon Posters
Poster # Topic Detector Date
2680-8 Determination of Free and Acylated
Glycerols in Biodiesel by HPLC-CAD Corona 03/12/2009
2730-26 Generic Approach to Analysis of
Pharmaceutical Salts Including
Inorganic and Organic Counter-ions. Corona 03/12/2009
600-9 Simultaneous Detection of a Broad
Range of Compounds in Pharmaceutical
Applications using a Single HPLC
Detector Corona 03/9/2009
2670-15 Analysis of Lipids by RP-HPLC Using
the Corona CAD Corona 03/12/2009
1630-5 The Evaluation of a New Family of
HPLC Columns for Use with Non-UV
Detectors Corona 03/10/2009
2730-1 Novel Analytical Approaches to
Aminoglycoside and Macrolide
Antibiotic Determination Corona & ECD 03/12/2009
2730-30 Sensitive Analysis of Aminopyridine
compounds using HPLC Electrochemical
Detection with a Boron-Doped Diamond
electrode ECD 03/12/2009
1990-11 Determination of Lactose in Milk by
HPLC with Corona CAD Corona 03/11/2009
1600-5 Simultaneous Cation and Anion
Analysis with Charged Aerosol
Detection Corona 03/10/2009
1600-6 Rapid Electrochemical Synthesis of
Oxidative Metabolites for Drug
Discovery ECD 03/10/2009
2290-15 Electrochemistry On-line with LC-MS
to Study Reactive Drug Metabolites ECD 03/11/2009
2290-3 Electrochemistry On-line with LC-MS to
Produce and Characterize Drug
Metabolites and Degradants ECD 03/11/2009
2730-2 High-throughput Estimation of Chemical
Stability to Oxidative Degradation of
Pharmaceutical Libraries Estimated by
HPLC-CoulArray Voltammetry ECD 03/12/2009
2290-1 Electrochemistry On-line with LC-MS
to Enhance Ionization and Selectivity
of LC-MS Analysis of Small Molecules ECD 03/11/2009
2290-2 Use of Coulometric Array in Parallel
with Mass Spectrometry as an
Orthogonal Detector in Pharmaceutical
Analysis ECD 03/11/2009
Customer Posters
600-7 Mass Balance Evaluation for Forced
Degradation of Digitoxin Using
HPLC-CAD (PPD) Corona 03/09/2009
2970-6 Development and Validation of
HPLC-Corona-CAD/UV Stability
Indicating Methods (Synomics) Corona 03/12/2009
1630-2 Applications of Polymer-Coated C18
Stationary Phase with Minimized
Column Bleeding to Liquid
Chromatography-Corona Charged
Aerosol Detection
(Shiseido Co., Ltd) Corona 03/10/2009
1650-7 Determination of Non-chromophoric
Small Molecule Organic Acids and
Bases Using Corona Charged Aerosol
Detector and Mass Spectrometry
Coupled with Various Stationary
Phases (Bristol Myer Squibb) Corona 03/10/2009
1590-4 Use of HPLC with Charged Aerosol
Detection for Quantification of
Biologically Relevant Oligosaccharides
(Sacramento State University) Corona 03/10/2009
